下面是引用xyzmoon于2005-12-20 19:13发表的:传说陈老师最终极的目标是子宫移植！！！！
对于移植，省立不是强项。
《国际妇产科杂志》2002年发表的一份研究报告表明，一位26岁的沙特妇女在2000年四月就已经在Jeddah医院研究中心接受了世界上迄今为止的首例子宫移植手术，她在20岁时曾因为严重的产后失血症而接受过子宫切除术。提供子宫者是一位46岁的妇女，因为患有卵巢囊肿而切除了未受影响的子宫。虽然手术后由于常见的并发症即子宫血管发生血液凝集而必须在三个月内将该移植的子宫再次切除掉，但支持者仍然认为这次移植还是成功的，并希望该突破将来能够用于帮助那些因某些损伤或疾病而不得不切除子宫的妇女在其育龄期间重新恢复生育能力。但是，许多专家却对这类移植手术的道德规范提出了质疑，因为对于维持妇女的生命来说子宫并非是必需的。和大多数器官移植一样，子宫移植接受者也必须接受强效抗排斥反应药物的处理，而后者显然会抑制其免疫系统功能，进而相应增加患某些严重疾病甚至发生死亡的危险。
International Journal of Gynecology & Obstetrics
Volume 76, Issue 3 , March 2002, Pages 245-251
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T7M-44V1YPM-4&_coverDate=03%2F31%2F2002&_alid=347940893&_rdoc=1&_fmt=&_orig=search&_qd=1&_cdi=5062&_sort=d&view=c&_acct=C000054345&_version=1&_urlVersion=0&_userid=1730128&md5=f70071124efaa92ed8bd60eabc0341d0Int J Gynaecol Obstet. 2002 Mar;76(3):245-51.
Transplantation of the human uterus.
Fageeh W, Raffa H, Jabbad H, Marzouki A.
Multiorgan Transplant Unit, King Fahad Hospital and Research Center, Jeddah, Saudi Arabia. w_
Fageeh@yahoo.comHuman uterine transplantation was performed on 6 April 2000 on a 26-year-old female who lost her uterus 6 years earlier due to post-partum hemorrhage. The donor, a 46-year-old patient with multiloculated ovarian cysts, underwent a hysterectomy modified to preserve tissue and vascular integrity. The donor uterus was connected in the orthotopic position to the recipient's vaginal vault and additional fixation was achieved by shortening the uterosacral ligament. The uterine arteries and veins were extended using reversed segments of the great saphenous vein, then connected to the external iliac arteries and veins, respectively. Immunosuppression was maintained by oral cyclosporine A (4 mg/kg/body wt.), azathioprine (1 mg/kg/body wt.) and prednisolone (0.2 mg/kg/body wt.). Allograft rejection was monitored by Echo-Doppler studies, magnetic resonance imaging (MRI), and measurement of the CD4/CD8 ratio in peripheral blood by fluorescence activated cell sorter (FACS scan). An episode of acute rejection was treated and controlled on the ninth day with anti-thymocytic globulin (ATG). The transplanted uterus responded well to combined estrogen--progesterone therapy, with endometrial proliferation up to 18 mm. The patient had two episodes of withdrawal bleeding upon cessation of the hormonal therapy. Unfortunately, she developed acute vascular thrombosis 99 days after transplantation, and hysterectomy was necessary. Macro- and microscopic histopathological examination revealed acute thrombosis in the vessels of the uterine body, with resulting infarction. Both fallopian tubes remained viable, however, with no evidence of rejection. The acute vascular occlusion appeared to be caused by inadequate uterine structure support, which led to probable tension, torsion, or kinking of the connected vascular uterine grafts.
