Research position is available at Brigham and Women's Hospital affiliated to Harvard Medical School.
We seek to understand why adult human brain circuits cannot regenerate their connection after damage. In particular, we focus on studying the axon, an often long process of a neuron that serves as its signaling wire.
Our current research applies mouse genetics, viral tools, imaging techniques, electrophysiological analysis and behavioral assessment. Current projects include attempts to regenerate optic nerve axons to restore vision and brain-spinal cord projecting axons for treating spinal cord injury.
PI: Fengfeng Bei and selected Publication:
1.Bei F*, Lee HH* , Liu X, Gunner G, Jin H, Ma L, Wang C, Hou L, Hensch TK, Frank E, Sanes JR, Chen C, Fagiolini M, He Z (2016). Restoration of visual function by enhancing conduction in regenerated axons. Cell164(1-2):219-232.
2. Duan X*, Qiao M*, Bei F*, Kim IJ, He Z, Sanes JR (2015). Subtype-specific regeneration of retinal ganglion cells following axotomy: effects of osteopontin and mTOR signaling. Neuron 85(6):1244-1256. (* co-first author)
3. Norsworthy MW*, Bei F*, Kawaguchi R, Wang Q, Tran NM, Li Y, Brommer B, Zhang Y, Wang C, Sanes JR, Coppola G, He Z. Sox11 Expression Promotes Regeneration of Some Retinal Ganglion Cell Types but Kills Others. Neuron. 2017 Jun 21;94(6):1112-1120.(co-first and corresponding Author)
We are looking for outstanding and highly motivated candidates who are interested in research, plan to apply Chinese Scholarship for 2 years.
Candidates with a background in electrophysiology, optic nerve and/or neurobiology are particularly welcome.
Interested people please send a copy of your CV to : fbei@bwh.harvard.edu