学历:
1993:医学学士(北京大学医学部,原北京医科大学);
1998:PhD (药理学),澳大利亚RMIT大学(导师Professor Michael Rand,Dr Chunguang Li,论文题目:Nitrergic Mechanisms in Cerebral Arteries)
工作经历:
2/1999-2/2005,博士后,澳大利亚墨尔本大学Howard Florey研究所
3/2005-6/2009 ,高级研究员,药理实验室主任,博士生导师,澳大利亚墨尔本大学Bernard O’Brien 研究所
9/2009,聘为山东大学齐鲁青年学者特聘教授,博士生导师
Recent publications:
1. Jiang, F. & Dusting, G.J. (2003) Natural phenolic compounds as cardiovascular therapeutics: potential role of their antiinflammatory effects. Curr. Vasc. Pharmacol., 1, 135-156. (IF 3.9)
2. Jiang, F., Guo, Y-N., Salvemini, D. & Dusting G.J. (2003) SOD Mimetic suppresses NADPH oxidase activity and improves endothelial function. Br. J. Pharmacol., 139, 1127-1134.
3. Jiang, F., Jones, G.T., Husband, A.J. & Dusting, G.J. (2003) Cardiovascular protective effects of synthetic isoflavone derivatives in apolipoprotein(E)-deficient mice. J. Vasc. Res., 40, 276-84.
4. Jiang, F., Drummond, G. & Dusting, G. (2004) Suppression of oxidative stress in the endothelium and vascular wall. Endothelium, 11(2), 79-88.
5. Dusting, G.J., Selemidis, S. & Jiang, F. (2005) Mechanisms for suppressing NADPH oxidase in the vascular wall. Memorias Instituto Oswaldo Cruz, 100 (Suppl 1), 97-103.
6. Jones, G.T., Jiang, F., McCormick S.P. & Dusting, GJ. (2005) Elastic lamina defects are an early feature of aortic lesions in the apolipoprotein E knockout mouse. J. Vasc. Res., 42(3), 237-46.
7. Moe, K.T., Aulia, S., Jiang, F., Chua, Y.L., Koh, T.H., Wong, M.C. and Dusting, G.J. (2006) Differential upregulation of Nox homologues of NADPH oxidase by tumor necrosis factor- in human aortic smooth muscle and embryonic kidney cells. J. Cell. Mol. Med., 10(1), 231-9.
8. Bilszta, J.L.C., Dusting, G.J. & Jiang, F. (2006) Arsenite increases vasoconstrictor reactivity in rat blood vessels: role of endothelial nitric oxide function. Int. J. Toxicol., 25(4), 303-10.
9. Jiang, F., Roberts, S.J., raju Datla, S. and Dusting, G.J. (2006) NO modulates NADPH oxidase function via heme oxygenase-1 in human endothelial cells. Hypertension, 48, 950-957.
10. Li, L., Yang, X., Jiang, F., Liu, A., Wu, Z. & Dusting, G.J. (2006) Evaluation of oxidative stress in experimental rabbit aneurysms. Zhongguo Yi Xue Ke Xue Yuan Xue Bao (Acta Academiae Medicinae Sinicae), 28(5), 707-709.
11. L Li , X Yang, GJ Dusting, A Liu, Z Wu, F Jiang. (2006) Expression and role of nitric oxide synthase in experimental aneurysms. Chin. J. Clin. Neurosurg., 11(12), 743-745.
12. SR Datla, GJ Dusting, TA Mori, CJ Taylor, KD Croft, F Jiang. (2007) Induction of heme oxygenase-1 in vivo suppresses NADPH oxidase-derived oxidative stress. Hypertension, 50(4): 636-42.
13. F Jiang, GT Jones and GJ Dusting. (2007) Failure of antioxidants to protect angiotensin II-induced aortic rupture in aged apolipoprotein(E)-deficient mice. Br. J. Pharmacol., 152(6): 880-890.
14. L Li, X Yang, GJ Dusting, Z Wu, F Jiang. (2007) Increased oxidative stress and xanthine oxidase activity in human ruptured cerebral aneurysms. Neuroradiol. J., 20(5): 545-550.
15. SR Datla, H Peshavariya, GJ Dusting, K Mahadev, BJ Goldstein, F Jiang. (2007) Important role of Nox4 type NADPH oxidase in angiogenic responses in human microvascular endothelial cells in vitro. Arterioscler Thromb Vasc Biol, 27: 2319-2324.
16. Jiang F, Guo N, Dusting GJ. (2007) Modulation of NADPH oxidase expression and function by 3',4'-dihydroxyflavonol in phagocytic and vascular cells. J. Pharmacol. Exp. Ther., 324(1):261-9.
17. F Jiang, G Zhang, I Hashimoto, BS Kumar, S Bortolotto, WA Morrison, GJ Dusting. (2008) Neovascularization in an arterio-venous loop-containing tissue engineering chamber: role of NADPH oxidase. J. Cell. Mol. Med., 12(5B): 2062-2072.
18. H Hachisuka, GJ Dusting, KM Abberton, WA Morrison, F Jiang. (2008) Role of NADPH oxidase in tissue growth in a tissue engineering chamber in rats. Journal of Tissue Engineering and Regenerative Medicine, 2(7):430-5.
19. F Jiang. (2009) NADPH oxidase in kidney: a Janus in determining cell fate. Kidney International, 75(2):135-7.
20. F Jiang, N Guo and GJ Dusting (2009). 3',4'-Dihydroxyflavonol suppresses monocyte chemoattractant protein-1 expression in vascular smooth muscle cells by inhibiting tyrosine kinase functions. Br. J. Pharmacol., accepted January.
21. EC Chan, F Jiang, HM Peshavariya & GJ Dusting (2009) Regulation of cell proliferation by NADPH oxidase-mediated signaling: potential roles in tissue repair, regenerative medicine and tissue engineering. Pharmacology & Therapeutics, 122(2): 97-108.
22. EC Chan, GT Jones, GJ Dusting, SR Datla, F Jiang. (2009) Prevention of aortic elastic lamina defects by losartan in apolipoprotein(E)-deficient mouse. Clin. Exp. Pharmacol. Physiol., accepted 23 Feb.
23. H Peshavariya, GJ Dusting, F Jiang, LR Halmos, CG Sobey, GR Drummond & S Selemidis. (2009) NADPH Oxiase isoform selective regulation of endothelial cell survival. Naunyn-Schmiedeberg Archives of Pharmacology. (accepted March)
24. H Peshavariya, F Jiang, CJ Taylor, CWT Chang, GJ Dusting. (2009) Translation-linked mRNA destabilization during serum-induced Nox4 expression in human endothelial cells. Antioxidants & Redox Signaling. (accepted March)
25. F. Jiang, A.J. Husband, G.J. Dusting. (2009) Isoflavone metabolites cis- and trans-tetrahydrodaidzein improve plasma lipid profile in apolipoprotein(E)-deficient mice. Open Complementary Medicine Journal, accepted August 2009.
26. Hitesh Peshavariya, Gregory J. Dusting, Belinda A. Di Bartolo, Kerry-Anne Rye, Philip J. Barter, and Fan Jiang. (2009) Reconstituted high-density lipoprotein suppresses leukocyte NADPH oxidase activation by disrupting lipid rafts. Free Radical Research, accepted June 2009.
27. L Li, X Yang, F Jiang , GJ Dusting, Z Wu. (2009) Transcriptome-wide characterization of gene expression associated with unruptured intracranial aneurysms. European Neurology, accepted July 2009.